Neural/immune related




Дата канвертавання24.04.2016
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Microarray Datasets for Comparative analysis of NIGO, GO and GO-slim
Microarray datasets downloaded from GEO at NCBI and used to test the performance of NIGO.


Neural/immune related

Experiment name

GEO accession

Experiment description

Gene Profile of RU486 effect on LPS induced gene expression in CNS [Mus musculus]

GSE6509

Gene expression microarray analysis was conducted using brain samples from mice treated with bacterial lipopolysaccharide (LPS) and glucocorticoid-receptor antagonist (RU486 – mifepristone) in comparison to samples taken from mice treated with LPS alone.

Astroglial gene expression program elicited by fibroblast growth factor-2 [Mus musculus]

GSE6675

Gene expression microarray analysis was conducted using astroglial cells treated with FGF2 in comparison to control samples.

Effect of chronic fluoxetine treatment on hippocampal gene expression [Mus musculus]

GSE6476

Gene expression microarray analysis was conducted using hippocampus of mice treated with fluoxetine in comparison to control samples.

p107 knockout vs. wild type neurospheres [mus musculus]

GSE3779

Gene expression microarray analysis was conducted using p107-/- neurospheres (cultured from the brain of E13.5 embroys) in comparison to wild type neurospheres.

Ras-GRF1 deficiency effect on the hippocampus [Mus musculus]

GSE8425


Gene expression microarray analysis was conducted using laser capture microdissected hippocampi of mutants lacking Ras-GRF1 in comparison to wild type.

ANA-1 macrophages infected with Chlamydia pneumoniae [Mus musculus]

GSE6690

Gene expression microarray analysis was conducted using mouse macrophages (ANA-1 cells) that were infected in vitro with C. pneumoniae with a M.O.I. of 10 in comparison to untreated macrophages.

Expression data from murine BRD2-mediated lymphomas [Mus musculus]

GSE6136

Gene expression microarray analysis was conducted using resting B-cells that are E-mu-BRD2 transgenic (aggressive lymphoma) in comparison to resting wild-type B-cells.

Comparison of gene expression pattern between Wild-type and Trib1-deficient mice [Mus musculus]


GSE8788

Gene expression microarray analysis was conducted using Trib1-deficient macrophages treated with LPS in comparison to wild-type macrophages treated with LPS.



Experiment name

GEO accession

Experiment description

Expression data for rat CNS mixed glial cultures treated with cytokines [Rattus norvegicus]

GSE9659

Gene expression microarray analysis was conducted using mixed CNS glia cultures from newborn rat brain were that were treated for 6 hours with a cytokine mixture representative of Th1 cytokines in comparison to mixed CNS glia cultures that were not treated.

Neural/immune unrelated

Experiment name

GEO accession

Experiment description

Regulation of Gene Expression by Sirt1 in the heart [Mus musculus]

GSE7407


Gene expression microarray analysis was conducted using the heart from transgenic mice with cardiac specific overexpression of Sirt1 (Tg-Sirt1) at 3 months of age in comparison to non-transgenic (NTg) control littermates.

Key stages in mammary gland development [mus musculus]

GSE8191


Gene expression microarray analysis was conducted using mammary glands from pregnant mice in comparison to mammary glands from lactating mice.

Androgen effect on spermatogenesis: time course [Mus musculus]

GSE2259

Gene expression microarray analysis was conducted using testis from sertoli cell-selective androgen receptor knockout (SCARKO) on postnatal d 10 in comparison to littermate controls.


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