Examples of drugs that may elevate liver enzymes Allopurinol




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Examples of drugs that may elevate liver enzymes

Allopurinol

ACE inhibitors

Amiodarone

Aspirin

Azathioprine



Carbimazole

Carbamazepine

Cefaclor

Chlorpromazine

Chlorpropamide

Cimetidine

Ciprofloxacin

Clofibrate

Co-amoxiclav

Cocaine


Co-trimoxazole

Cyclophosphamide

Cyproterone

Dantrolene

Diclofenac

Didanosine

Diltiazem

Donepezil

Ecstasy

Efavirenz

Erythromycin

Flucloxacillin

Flutamide

Fusidic acid

Gold

Halothane



Heparin/ LWMH

Hydralazine

Iron (overdose)

Ketaconazole

Labetalol

Leflunomide

Methotrexate

Methyldopa

Minocycline

Monoamine oxidase inhibitors

Nitrofurantoin

Nevirapine

Non steroidal anti-inflammatory drugs

Paracetamol

Penicillin

Penicillamine

Phenindione

Phenoxybutazone

Phenytoin

Pioglitazone

Procainamide

Propafenone

Propylthiouracil

Quinidine

Quinine

Ranitidine



Serotonin reuptake inhibitors

Statins


Sulphasalazine

Sulphonamides

Sulphonylureas

Tamoxifen

Tetracycline

TPN


Trazodone

Tricyclic antidepressants

Vitamin A (overdose)
Herbal preparations associated with liver damage
Black Cohosh

Borage oil

Camellia Sinensis

Chapparal (Larrea tridentata)

Chinese herbal preparations for skin disorders

Comfrey


Fortorol (food supplement whichh may contain nimesulide)

Garcinia (Garcinia camboge)

Germander (Teucrium chamaedrys)

Hydroxycut

Kava kava (Piper methysticum)

Khat (Catha edulis)

Miradin (food supplement whichh may contain nimesulide)

Mistletoe (skullcap)

Noni Juice (Morina citrofolia)

Passion flower (Passiflora incarnata)

Pennyroyal

Ubiquinone

Valerian (Valeriana Officinalis)

Bridget Featherstone October 2011


Referenes

1. Featherstone B 2011. Adverse effects of drugs on the liver. In R Walker and C Whittlesea Eds. Clinical Pharmacy and Therapeutics 5th Edition. Chapter 15. Churchill Livingstone Elsevier.



2. Forrest E. 2006. Hepatic Disorders. In Anne Lee Ed. Adverse Drug Reactions. 2nd Edition Chapter 7.. Pharmaceutical Press


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