Dr. R. Manjunatha Kini List of Publications patents 1-15. Evans, H. J. and Kini, R. M




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Kini, R. M., Jacob, B. and Joseph, J. S.: Development of novel class of anticoagulant peptides based on the structure of prothrombin activator from Tropidechis carinatus venom. Venoms to Drugs held at Heron Island, Australia 2002.




  1. Rajaseger, G., Moochhala, S., Yeo, J., Lu, J., and Kini, R. M.: Purification and toxiocological characterization of bucarin, a helveprin from Bungarus candidus (Malayan krait) venom. Venoms to Drugs held at Heron Island, Australia 2002.




  1. Fry, B.G., Wuster, W., Kini, R.M., Brusic, V., Khan, A., Venkataraman, D. and Rooney, A.: The three finger toxin toolkit. Venoms to Drugs held at Heron Island, Australia 2002.




  1. Kini, R.M.: Structure-function relationships of a prothrombin activator from snake venom: Development of anticoagulant peptides. First NUS-University of Sydney Bilateral Symposium on Advances in Molecular Biotechnology and Biomedicine held in Singapore 2002.




  1. Pung, Y.F. and Kini, R.M.: Purification and partial charaterization of a novel protein from Ophiophagus hannah (Bali King cobra). First NUS-University of Sydney Bilateral Symposium on Advances in Molecular Biotechnology and Biomedicine held in Singapore 2002.




  1. Rao, V. S., Joseph, J. S., and Kini R. M.: Group D prothrombin activators from snake venom are structural homologues of mammalian factor Xa. First NUS-University of Sydney Bilateral Symposium on Advances in Molecular Biotechnology and Biomedicine held in Singapore 2002.




  1. Torres, A. M., Desai, M., Ying, W. H., Kini, R. M. and Kuchel, P. W.: Structure of nawaprin, a member of new family of snake venom proteins. Second International Conference on Structural Biology and Functional Genomics held in Singapore, 2002.




  1. Vivekanandan, S., Ajikumar, P. K., Lakshminarayanan, R., Jois, S. D. S., Valiyaveettil, S. and Kini, R. M.: Solution structure of designed peptides that induce calcite crystal aggregation. Second International Conference on Structural Biology and Functional Genomics held in Singapore, 2002.




  1. Vivekanandan, S., Ge, R., Jois, S. D. S. and Kini, R. M.: NMR studies of a small peptide derived from human kringle domain 3. Second International Conference on Structural Biology and Functional Genomics held in Singapore, 2002.




  1. Paaventhan, P., Joseph, J. S., Nirthanan, S., G. Rajaseger, Kini, R. M. and Kolatkar, P. K.: Crystallization and preliminary X-ray analysis of candoxin, a novel weak neurotoxin from the Malayan krait Bungarus candidus. Second International Conference on Structural Biology and Functional Genomics held in Singapore, 2002.




  1. Rao, V. S., Joseph, J. S. and Kini, R. M.: Comparative molecular modeling of the nonenzymatic subunit of pseutarin C, a prothrombin activator from the venom of Australian brown snake. Second International Conference on Structural Biology and Functional Genomics held in Singapore, 2002.




  1. Lakshminarayanan, R., Valiyaveettil, S., Rao, V. S. and Kini, R. M.: Comparative study of structure-function relationship of eggshell proteins. Second International Conference on Structural Biology and Functional Genomics held in Singapore, 2002.




  1. Sivaraman, T. and Kini, R. M.: NMR studies of bungatoxin: 1H resonances assignment and structural analysis. Second International Conference on Structural Biology and Functional Genomics held in Singapore, 2002.




  1. Sivaraman, T. and Kini, R. M.: Structure and folding of buntoxin, a novel protein toxin purified from Bungarus candidus venom. Second International Conference on Structural Biology and Functional Genomics held in Singapore, 2002.




  1. Jacob, B., Joseph, J. S. and Kini, R. M.: Interaction of novel anticoagulant peptides with blood coagulation factor Va. Annual Indian Biophysical Society meeting held in Rourkee, India, 2003.




  1. Rao, V. S., Swarup, S. and Kini R. M.: cDNA sequence of the nonenzymatic subunit of pseutarin C, a prothrombin activator from the eastern brown snake (Pseudonaja textilis): its structural similarity to blood coagulation factor V. XIX Congress of the International Society on Thrombosis and Haemostasis held in Birmingham, UK, 2003.




  1. Rao, V. S., Joseph, J. S. and Kini R. M.: Comparative molecular modeling of the nonenzymatic subunit of pseutarin C, a prothrombin activator from the venom of eastern brown snake. XIX Congress of the International Society on Thrombosis and Haemostasis held in Birmingham, UK, 2003.




  1. Rao, V. S., Swarup, S. and Kini R. M.: The catalytic subunit of pseutarin C, a group C prothrombin activator from Pseudonaja textilis is structurally similar to blood coagulation factor X. XIX Congress of the International Society on Thrombosis and Haemostasis held in Birmingham, UK, 2003.




  1. Kini R. M., Jacob B. and Joseph, J. S.: Structure-function relationships of trocarin, a prothrombin activator from Tropidechis carinatus venom: development of novel class of anticoagulant peptides. 9th Southeast Asian-Western Pacific Regional Meeting of Pharmacologists held in Busan, Korea, 2003.




  1. Kini, R. M.: Prothrombin activators from snake venoms. XIV World Congress on Animal, Plant and Microbial Toxins held in Adelaide, Australia, 2003.




  1. Kang, T. S. and Kini, R. M.: Engineering of a Conus toxin into a potent IIb3 inhibitor. XIV World Congress on Animal, Plant and Microbial Toxins held in Adelaide, Australia, 2003.




  1. Dileep, G. R., Fry, B. G., Kumar, P. P. and Kini, R. M.: Expression of omwaprin in E. coli, a member of waprin family of snake venom proteins. XIV World Congress on Animal, Plant and Microbial Toxins held in Adelaide, Australia, 2003.




  1. Reza, M. A. and Kini, R. M.: cDNA sequence of factor X of Australian rough scale snake Tropidechis carinatus and its comparison with the venom prothrombin activator, trocarin D. XIV World Congress on Animal, Plant and Microbial Toxins held in Adelaide, Australia, 2003.




  1. Banerjee, Y. and Kini, R. M.: Isolation and characterization of anticoagulant protein from the venom of Hemachatus haemachatus. XIV World Congress on Animal, Plant and Microbial Toxins held in Adelaide, Australia, 2003.




  1. Pawlak, J., Fry, B. G. and Kini, R. M.: Cloning and expression of the cDNA encoding a novel three-finger toxin in Boiga dendrophila (Mangrove snake) venom. XIV World Congress on Animal, Plant and Microbial Toxins held in Adelaide, Australia, 2003.




  1. Rehana, S. and Kini, R. M.: Isolation and characterization of a novel protein from the venom of Austrelaps superbus. XIV World Congress on Animal, Plant and Microbial Toxins held in Adelaide, Australia, 2003.




  1. Nandhakishore, R., Pung, Y. F., Kumar, P. P. and Kini, R. M.: Identification of small toxin genes from the venom gland of Ophiophagus hannah using ESTs approach. XIV World Congress on Animal, Plant and Microbial Toxins held in Adelaide, Australia, 2003.




  1. Lumsden, N. G., Fry, B. G., Kini, R. M. and Hodgson, W. C.: The in vitro neurotoxicity of venoms from ‘harmless’ snakes. XIV World Congress on Animal, Plant and Microbial Toxins held in Adelaide, Australia, 2003.




  1. Lumsden, N. G., Fry, B. G., Kini, R. M. and Hodgson, W. C.: Smooth muscle activity of Boiga venoms. XIV World Congress on Animal, Plant and Microbial Toxins held in Adelaide, Australia, 2003.




  1. Fry, B. G., Lumsden, N. G., Hodgson, W. C., Kini, R. M. and Wüster, W.: The molecular evolution of Colubroidea snake venoms. XIV World Congress on Animal, Plant and Microbial Toxins held in Adelaide, Australia, 2003.




  1. Mackessy, S. P. and Kini, R. M.: Isolation and characterization of Tigrinobin, a serine protease with thrombin like activity, from the venom of the Tiger Rattlesnake (Crotalus tigris). XIV World IST Congress on Animal, Plant & Microbial Toxins held in Adelaide, Australia, 2003.




  1. Reza, M. A. and Kini, R. M.: Blood Coagulation Factor Resembles Venom Prothrombin Activator of Australian Rough Scaled snake Tropidechis carinatus. Fourth Sino-Singapore Conference in Biotechnology held in Singapore, 2003.




  1. Le, T. N. M., Reza, M. A., Swarup, S. and Kini, R. M.: Structural comparison between venom and liver factor V in Pseudonaja textilis. Fourth Sino-Singapore Conference in Biotechnology held in Singapore, 2003.




  1. Pawlak, J., Fry, B. G. and Kini, R. M.: Cloning and expression of the cDNA encoding a novel three-finger toxin in Boiga dendrophila (Mangrove snake) venom. Fourth Sino-Singapore Conference in Biotechnology held in Singapore, 2003




  1. Dileep, G. R, Fry, B. G., Kumar, P. P and Kini, R. M.: Expression of Omwaprin in E. coli, a Member of Waprin Family of Snake Venom Proteins. Fourth Sino-Singapore Conference in Biotechnology held in Singapore, 2003.




  1. Kini, R. M.: Prothrombin activators from snake venoms and their structural similarity to blood coagulation factors. Third National Symposium on Venoms and Toxins held in Mysore, India, 2004.




  1. Kini, R. M.: Research on snake venom toxins: a lot of fun and excitement. Third National Symposium on Venoms and Toxins held in Mysore, India, 2004.




  1. Kini, R. M.: Serine proteinases affecting blood coagulation and fibrinolysis from snake venom. XVII International Congress on Fibrinolysis and Proteolysis held in Melbourne, Australia, 2004.




  1. Kini, R. M.: Exogenous and endogenous prothrombin activator systems in Australian snakes. 50th Scientific and Standardization Committee Meeting of the International Society on Thrombosis and Haemostasis held in Venice, Italy, 2004.




  1. Kini, R. M., Reza M. A. and Le T. N. M.: Two parallel prothrombin activator systems in Australian snakes. 15th European Symposium on Animal, Plant and Microbial Toxins held in Brdo, Slovenia, 2004.




  1. Kini, R. M.: Search for new toxins from snake venoms. VIII Symposium of the Pan American Society on Toxinology and VIII Congress of Brazilian Society of Toxinology held in Angra dos Reis, Rio de Janeiro, Brazil, 2004.




  1. Kini, R. M.: Prothrombin activators from snake venoms. Third Asia-Pacific Congress on Thrombosis and Hemostasis held in Bangkok, Thailand, 2004.




  1. Kini, R. M.: Parallel prothrombin activator systems in Australian snakes. 5th Sino-Singapore Conference on Life Science and Biotechnology held in Wuhan, China, 2004.




  1. Kini, R. M.: Prothrombin activators in Australian snakes. Third International Conference on Structural Biology and Functional Genomics held at Singapore, 2004.




  1. Le, T. N. M., Reza, M. A. and Kini, R. M.: Two parallel prothrombin activator systems in snakes. Third International Conference on Structural Biology and Functional Genomics held at Singapore, 2004. Second prize for Outstanding Poster




  1. Li, M, Fry, B. G. and Kini, R. M.: Putting the brakes on snake venom evolution: the unique molecular evolutionary patterns of Aipysurus eydouxii (Marbled sea snake) Phospholipase A2 toxins. Third International Conference on Structural Biology and Functional Genomics held at Singapore, 2004.




  1. Nandhakishore, R., Pung, Y. F., Kumar, P. P., and Kini R. M.: Identification, expression and preliminary studies of three novel toxin proteins from the venom of Ophiophagus hannah. Third International Conference on Structural Biology and Functional Genomics, Singapore 2004.




  1. Kang, T. S., Jois, S. D. S. and Kini R. M.: Structural Features affecting the folding of IMI Conotoxin. Third International Conference on Structural Biology and Functional Genomics held at Singapore, 2004




  1. Nandhakishore, R., Pung, Y. F., Kumar, P. P. and Kini, R. M.: Recombinant production and functional studies of venom proteins from Ophiophagus hannah. Biology in Asia International Conference held at Singapore, 2004.

167. Kini, R. M.: Anticoagulant proteins from snake venoms. 51st Scientific and Standardization Committee Meeting of the International Society on Thrombosis and Haemostasis held in Sydney, Australia, 2005.


168. Kini, R. M.: Prothrombin Activators from Snake Venoms Similar to Mammalian Blood Coagulation Factors. XX Congress of the International Society on Thrombosis and Haemostasis held in Sydney, Australia, 2005.
169. Reza, M. A., Swarup, S. and Kini, R. M.: Two Isoforms of Factor X Is Produced in the Liver of Pseudonaja textilis. XX Congress of the International Society on Thrombosis and Haemostasis held in Sydney, Australia, 2005.
170. Reza, M. A., Swarup, S. and Kini, R. M.: Gene Structures of Two Functionally Diverse Prothrombin Activators, Trocarin D and Coagulation Factor X, in Tropidechis carinatus Snake. XX Congress of the International Society on Thrombosis and Haemostasis held in Sydney, Australia, 2005.
171. Banerjee, Y. and Kini, R. M.: A Novel Anticoagulant Protein – Hemextin A, from the Venom of Hemachatus haemachatus (African Ringhals Cobra) That inhibits the Extrinsic Tenase Activity and Its Synergistic Interaction with A Three-finger Toxin, Hemextin B. XX Congress of the International Society on Thrombosis and Haemostasis held in Sydney, Australia, 2005.
172. Le, T. N. M., Reza, M. A., Swarup, S. and Kini, R. M.: Two Parallel Prothrombin Activator Systems in Eastern Brown Snakes. XX Congress of the International Society on Thrombosis and Haemostasis held in Sydney, Australia, 2005.
173. Kini, R. M.: Serine Proteinases Affecting Blood Coagulation and Fibrinolysis from Snake Venom. Third International Congress on the Exogenous Factors affecting Thrombosis and Haemostasis held in Sydney, Australia, 2005.
174. Banerjee, Y., Mizuguchi, J., Iwanaga, S. and Kini, R. M.: Hemextin AB complex – a snake venom anticoagulant protein complex that inhibits factor VIIa activity. Third International Congress on the Exogenous Factors affecting Thrombosis and Haemostasis held in Sydney, Australia, 2005.
175. Reza, M. A., Swarup, S. and Kini, R. M.: Gene Structures of Trocarin D and Coagulation Factor X, Two Functionally Diverse Prothrombin Activators from Australian Rough Scaled Snake. Third International Congress on the Exogenous Factors affecting Thrombosis and Haemostasis held in Sydney, Australia, 2005.
176. Kini, R. M.: From toxins to therapeutics: Development of therapeutic agents based on the structure of snake venom toxins. Pharma Indochina IV Conference held in Ho Chi Minh City, Viet Nam, 2005.
177. Kini, R. M.: Toxin folds in snake venom proteins. XV World Congress on Animal, Plant and Microbial Toxins held in Glasgow, UK, 2006.
178. Kini, R. M.: Origin and evolution of snake venom prothrombin activators. XV World Congress on Animal, Plant and Microbial Toxins held in Glasgow, UK, 2006.



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