Dr. R. Manjunatha Kini List of Publications patents 1-15. Evans, H. J. and Kini, R. M




старонка1/3
Дата канвертавання24.04.2016
Памер184.02 Kb.
  1   2   3
Dr. R. Manjunatha Kini - List of Publications
PATENTS
1-15. Evans, H. J. and Kini, R. M.: Polypeptides that include conformation-constraining groups which flank a protein-protein interaction site. U. S. patents 5,928,896; 5,948,887; 5,952,465; 5,965,698; 6,084,066; 6,100,044; 6,111,069; 6,147,189; 6,258,550; several others pending.
16. Gopalakrishnakone, P., Pu, X. C., Wong, P. T. H., Gwee, M. C. E. and Kini, R. M.: Therapeutic molecules derived from snake venom. U. S. patent 6,613,745. Singapore patent application under consideration.
17-18. Kini, R. M., Subburaju, S. and Chow, G. L. S.: Novel protein molecules and uses therefor. U. S. Patent 6,075,129. Singapore patent 81920.
19. Gopalakrishnakone, P., Kini, R. M. and Huang, M. Z.: Novel anti-clotting molecules and uses therefor. Singapore patent application under consideration.
20. Kini, R. M., Jeyaseelan, K., Jeramiah Joseph, Armugam, A. and Mirtschin, P.: Snake venom enzymes as tools in molecular biology. Singapore patent application under consideration.
21. Chen, S. H., Kini, R. M. and Dong Hui: A method for inhibiting clot formation. Singapore patent 81245.
22-23. Ge, R. and Kini, R. M.: Small peptides having potent anti-angiogenic activity. US Patent 6,200,954; Other application pending.
24. Kang, T. S. and Kini, R. M.: Conformational Switches in toxin folding and uses thereof. US Patent Application No. 60/608,151.
25. Kini, R. M., Kumar, P. P., Wong, P. T. H. and Pung, Y. F.: Novel Snake Toxin. US Patent Application No. 60/639,345
26. Kini, R. M. and Banerjee, Y.: Novel anticoagulant polypeptides and complex. US Patent Application No. 60/706,250.
27. Ge, R. and Kini, R. M.: Compounds and uses thereof. Singapore Patent Application 200403034-2; US Patent Application pending.
28. Kini, R. M., Reza, M. A. and Swarup, S.: Novel promoter sequences for elevated protein expression in mammalian system US provisional Application filed.
RESEARCH PUBLICATIONS
Doctoral Thesis:
Studies on the effects of a plant isolate on snake venom enzymes. University of Mysore, Mysore, INDIA, 1983.
Books/ Special Issues:
Venom Phospholipase A2 Enzymes: Structure, Function and Mechanism (Kini, R. M., Editor), pp. 1-511, John Wiley & Sons, Chichester, England, 1997.
International Conference on Exogenous Factors Affecting Thrombosis and Haemostasis (Bon, C., Kini, R. M., Markland, F. S., Marsh, N. A. and Rosing, J., Editors), Haemostasis Vol. 31, pp. 117-311, S. Karger, Basel, Switzerland, 2002.
Exogenous Factors Affecting Thrombosis and Hemostasis (Kini, R. M., Guest Editor), Current Drug Targets – Cardiovascular and Hematologic Disorders. Bentham Publishers, 2004.
Exogenous Factors Affecting Thrombosis and Haemostasis (Kini, R. M., Marsh, N. A., Markland, F. S. and Broady, K. W., Editors), Pathophysiology of Haemostasis and Thrombosis Vol. 34, pp.145-248, S. Karger, Basel, Switzerland, 2005.

Journal Papers:
1. Kini, R.M. and Gowda, T.V.: Single-step fractionation of Vipera russelli venom. A sensitive fluorimetric method to study the elution profile. J. Chromatogr., 216, 395 398, 1981.
2. Kini, R.M. and Gowda, T.V.: Studies on snake venom enzymes: Part I Purification of ATPase, a toxic component of Naja naja venom and its interaction with potassium gymnemate. Indian J. Biochem. Biophys., 19, 152 154, 1982.

3. Kini, R.M. and Gowda, T.V.: Studies on snake venom enzymes: Part II Partial characterization of ATPases from Russell's viper (Vipera russelli) venom and their interaction with potassium gymnemate. Indian J. Biochem. Biophys., 19, 342 346, 1982.

4. Kini, R.M. and Gowda, T.V.: Modification single step separation procedure for several protein constituents of venom of Indian cobra (Naja naja). Curr. Sci., 52, 70 71, 1983.

5. Kini, R.M. and Gowda, T.V.: A rapid method for separation and purification of four isoenzymes of phosphodiesterase from Trimeresurus flavoviridis (habu snake) venom. J. Chromatogr., 291, 299 305, 1984.

6. Kini, R.M. and Iwanaga, S.: Structure function relationships of phospholipases I: Prediction of presynaptic neurotoxicity. Toxicon, 24, 527 541, 1986.

7. Kini, R.M. and Iwanaga, S.: Structure function relationships of phospholipases II: Charge density distribution and the myotoxicity of presynaptically neurotoxic phospholipases. Toxicon, 24, 895 905, 1986.

8. Kini, R.M., Kawabata,S. and Iwanaga, S.: Comparison of amino terminal region three isoenzymes of phospholipases A2 (TFV PL Ia, TFV PL Ib AND TFV PL X) from Trimeresurus flavoviridis (habu snake) venom and the complete amino acid sequence of the basic phospholipase, TFV PL X. Toxicon 24, 1117 1129, 1986.
9. Vishwanath, B.S., Kini, R.M. and Gowda, T.V.: Characterization of three edema inducing phospholipase A2 enzymes from habu (Trimeresurus flavoviridis) venom and their interaction with an alkaloid, aristalochic acid. Toxicon 25, 501 515, 1987.
10. Kini, R.M. and Evans, H.J.: Structure function relationships of phospholipases: The anticoagulant region of phospholipases A2. J. Biol. Chem., 262, 14402 14407, 1987.

11. Kini, R.M., Haar, N.C. and Evans, H.J.: Non enzymatic inhibitors of coagulation and platelet aggregation from Naja nigricollis venom are cardiotoxins. Biochem. Biophys. Res. Commun., 150, 1012 1016, 1988.

12. Vishwanath, B.S., Kini, R.M. and Gowda, T.V.: Purification and partial biochemical characterization of an edema inducing phospholipase A2 from Vipera russelli (Russell's viper) snake venom. Toxicon, 26, 713 720, 1988.

13. Kini, R.M. and Evans, H.J.: Correlation between the enzymatic activity, anticoagulant and antiplatelet effects of phospholipase A2 isoenzymes from Naja nigricollis venom. Thrombos. Haemos., 60, 170 173, 1988.

14. Kini, R.M. and Evans, H.J.: Mechanism of platelet effects of cardiotoxins from Naja nigricollis crawshawii (spitting cobra) snake venom. Thrombos. Res., 52, 185 195, 1988.
15. Kini, R.M. and Evans, H.J.: A model to explain the pharmacological effects of snake venom phospholipases A2. Toxicon, 27, 613 635, 1989.

16. Kini, R.M. and Evans, H.J.: A common cytolytic region in myotoxins, hemolysins, cardiotoxins and antibacterial peptides. Int. J. Peptide Protein Res., 34, 277 286, 1989.

17. Stefansson, S., Kini, R.M. and Evans, H.J.: The inhibition of clotting complexes of the extrinsic coagulation cascade by the phospholipase A2 isoenzymes from Naja nigricollis venom. Thrombos. Res., 55, 481 491, 1989.
18. Kini, R.M. and Evans, H.J.: Role of cationic amino acid residues in cytolytic activity. Modifications of lysine residues in the cardiotoxin from Naja nigricollis venom and correlation between cytolytic and antiplatelet activities. Biochemistry, 28, 9209-9215, 1989.

19. Stefansson, S., Kini, R.M. and Evans, H.J.: The basic phospholipase A2 from Naja nigricollis venom inhibits the prothrombinase complex by a novel nonenzymatic mechanism. Biochemistry, 29, 7742-7746, 1990.


20. Kini, R.M. and Evans, H.J.: Inhibition of platelet aggregation by a fibrinogenase from Naja nigricollis venom is independent of fibrinogen degradation. Biochim. Biophys. Acta, 1095, 117-121, 1991.
21. Kini, R.M. and Evans, H.J.: Molecular modeling of proteins: A strategy for energy minimization by molecular mechanics in the AMBER force field. J. Biomolec. Struc. Dyn., 9, 475-488, 1991.

22. Kini, R.M. and Evans, H.J.: Structural domains in venom proteins: evidence that metalloproteinases and nonenzymatic aggregation inhibitors (disintegrins) from snake venoms are derived by proteolysis from a common precursor. Toxicon, 30, 265-293, 1992.


23. Kini, R. M. and Evans, H. J.: Comparison of protein models minimized by the all-atom and united-atom models in the AMBER force field: correlation of RMS deviation with the crystallographic R factor and size. J. Biomolec. Struc. Dyn., 10, 265-279, 1992.
24. Kini, R. M.: Do we know the complete sequence of metalloproteinase and nonenzymatic platelet aggregation inhibitor (disintegrin) precursor proteins? Toxicon, 33, 1151-1160, 1995.
25. Kini, R. M. and Evans, H. J.: A hypothetical structural role for proline residues in the flanking segments of protein-protein interaction sites. Biochem. Biophys. Res. Commun., 212, 1115-1124, 1995.
26. Kini, R. M. and Evans, H. J.: The role of enzymatic activity in inhibition of the extrinsic tenase complex by phospholipase A2 isoenzymes from Naja nigricollis venom. Toxicon, 33, 1585-1590, 1995.
27. Kini, R. M. and Evans, H. J.: A novel approach to the design of potent bioactive peptides by incorporation of proline brackets: antiplatelet effects of Arg-Gly-Asp peptides. FEBS Lett., 375, 15-17, 1995.
28. Kini, R. M. and Evans, H. J.: Prediction of potential protein-protein interaction sites from amino acid sequence. Identification of a fibrin polymerization site. FEBS Lett., 385, 81-86, 1996.
29. Ghadessy, F. J., Chen, D., Kini, R. M., Chung, M. C. M., Jeyaseelan, K., Khoo, H. E. and Yuen, R.: Stonustoxin: a novel lethal factor from stonefish (Synanceja horrida) venom. cDNA cloning and characterization. J. Biol. Chem., 271, 25575-25581, 1996.
30. Kini, R. M.: Are C-type lectin-related proteins derived by proteolysis of metalloproteinase/disintegrin precursor proteins? Toxicon, 34, 1287-1294, 1996.
31. Kini, R. M., Zhang, C. Y. and Tan, B. K. H.: Pharmacological activity of the interdomain segment between metalloproteinase and disintegrin domains. Toxicon, 35, 529-535, 1997.
32. Huang, M. Z., Gopalakrishnakone, P., Chung, M. C. M. and Kini, R. M.: Complete amino acid sequence of an acidic, cardiotoxic phospholipase A2 from the venom of Ophiophagus hannah (King cobra): a novel cobra venom enzyme with “pancreatic loop”. Arch. Biochem. Biophys., 338, 150-156, 1997 (COVER for Volumes 339 and 240).
33. Huang, Y., Tan, J. M. W. L., Kini, R. M. and Ho, S. H.: Toxic and antifeedant action of nutmeg oil against Tribolium castaneum (Herbst) and Sitophilus zeamais Motsch. J. Stored Products Res., 33, 289-298, 1997.
34. Gong, J. P., Kini, R. M., Gwee, M. C. W., Gopalakrishnakone, P. and Chung, M. C. M.: Makatoxin I, a novel toxin isolated from the venom of scorpion Buthus martens Karsch, exhibits nitrergic actions. J. Biol. Chem., 272, 8320-8324, 1997.
35. Subburaju, S. and Kini, R. M.: Isolation and purification of superbins I and II from Austrelaps superbus (copperhead) snake venom and their anticoagulant and antiplatelet effects. Toxicon, 35, 1239-1250, 1997.
36. Chen, D. S., Kini, R. M., Yuen, R. and Khoo, H. E.: Haemolytic activity of stonustoxin from stonefish (Synanceja horrida) venom. Pore formation and the role of cationic amino acid residues. Biochem. J. 325, 685-691, 1997.
37. Huang, M. Z., Gopalakrishnakone, P. and Kini, R. M.: Antiplatelet effects of a phospholipase A2 (OHV A-PLA2) from the venom of Ophiophagus hannah (King cobra): role of platelet secretion. Life Sci., 61, 2211-2217, 1997.
38. Gong, J. P., Gwee, M. C. W., Gopalakrishnakone, P., Kini, R. M. and Chung, M. C. M.: Adrenergic and nitrergic responses of the rat isolated anococcygeus muscle to a new toxin (Makatoxin I) from the venom of the scorpion Buthus martensii Karsch. J. Autonomic Pharmacol., 17, 129-135, 1997.
39. Kini, R. M., Caldwell, R. A., Wu, Q. Y., Baumgarten, C. M., Feher, J. J. and Evans, H. J.: Flanking proline residues identify the L-type Ca2+ channel binding site of calciseptine and FS2. Biochemistry 37, 9058-9063, 1998.
40. Chow, G., Subburaju, S. and Kini, R. M.: Purification and amino acid sequence determination of acanthins, potent inhibitors of platelet aggregation from Acanthophis antarcticus (common death adder) venom. Arch. Biochem. Biophys. 354, 232-238, 1998.


  1. Ngoh, S. P., Choo, L. E. W., Pang, F. Y., Huang, Y., Kini, R. M. and Ho, S. H.: Insecticidal and repellant properties of nine volatile constituents of essential oils against the American cockroach, Periplaneta americana (L.). Pesticide Sci. 54, 261-268, 1998.

42. Dong, H., Chen, S. X., Kini, R. M. and Xu, H. X.: Effects of tannins from Geum japonicum on the catalytic activity of thrombin and factor Xa of blood coagulation cascade. J. Nat. Products, 61, 1356-1360, 1998.


43. Pwee, K. H., Ooi, S. J. and Kini, R. M.: Isolation, partial purification and differential DNA-binding properties of high-mobility-group (HMG) proteins from rice. Plant Science, 139, 117-129, 1998.
44. Kini, R. M. and Chan, Y. M.: Accelerated evolution and molecular surface of venom phospholipase A2 enzymes. J. Mol. Evol. 48, 125-132, 1999.
45. Dong, H., Gou, Y. L., Cao, S. G., Chen, S. X., Sim, K. Y., Goh, S. H. and Kini, R. M.: Eicosanoids and methylated flavonols from Amomum koenigii. Phytochemistry, 50, 899-902, 1999.
46. Joseph, J. S., Chung, M. C. M., Jeyaseelan, K. and Kini, R. M.: Amino acid sequence of trocarin, a prothrombin activator from Tropidechis carinatus venom: Its structural similarity to coagulation factor Xa. Blood, 94, 621-631, 1999.
47. Huang, Y., Ho, S. H. and Kini, R. M.: Bioactivities of safrole and isosafrole on Sitophilus zeamais (Coleoptera: Curculionidae) and Tribolium castaneum (Coleoptera: Tenebrionidae). J. Economic Entomol. 92, 676-683, 1999.
48. Wang, R., Kini, R. M. and Chung, M. C. M.: Rhodocetin, a novel platelet aggregation inhibitor from the venom of Calloselasma rhodostoma (Malayan pit viper). Synergistic and noncovalent interaction between its subunits. Biochemistry, 38, 7584-7593, 1999.
49. Kerns, R. T., Kini, R. M., Stefansson, S. and Evans, H. J.: Targeting of venom phospholipases: the strongly anticoagulant phospholipase A2 from Naja nigricollis venom binds to coagulation factor Xa to inhibit the prothrombinase complex. Arch. Biochem. Biophys. 369, 107-113, 1999.
50. Gao, R., Kini, R. M. and Gopalakrishnakone, P.: Purification, properties and amino acid sequence of a haemoglobinuria-inducing phospholipase A2, MiPLA-1 from Micropechis ikaheka venom. Arch. Biochem. Biophys. 369, 181-192, 1999.
51. Hirpara, J. L., Ali, S. M., Dong, H., Kini, R. M. and Pervaiz, S.: Induction of mitochondrial permeability transition and cytochrome C release in the absence of caspase activation is not sufficient for effective apoptosis in human leukemia cells. Blood, 95, 1773-1780, 2000.
52. Tan, S. W. L., Wong, S. M. and Kini, R. M.: Rapid simultaneous detection of two orchid viruses using LC- and/or MALDI-mass spectrometry. J. Virological Meth. 85, 93-99, 2000.
53. Singh, B. S., Armugam, A., Kini, R. M. and Jeyaseelan, K.: Phospholipase A2 with platelet aggregation inhibitor activity from Austrelaps superbus venom: protein purification and cDNA cloning. Arch. Biochem. Biophys. 375, 289-303, 2000.
54. Thwin, M. M., Gopalakrishnakone, P., Kini, R. M., Armugam, A. and Jeyaseelan, K.: Recombinant antitoxic and anti-inflammatory factor from nonvenomous snake, Python reticulatus: phospholipase A2 inhibition and therapeutic potential. Biochemistry 39, 9604-9611, 2000.
55. Balaji, R. A., Sasaki, T., Gopalakrishnakone, P., Sato, K., Kini, R. M. and Bay, B. H.: Purification, structure determination and synthesis of covalitoxin-II, a short insect-specific neurotoxic peptide from the venom of the Coremiocnemis validus (Singapore tarantula). FEBS Lett. 474, 208-212, 2000.
56. Parvathy V. R., Chary, K. V. R., Kini, R. M. and Govil, G.: NMR studies of a neurotoxin (candoxin) from Bungarus candidus – Presence of predominantly sheet structure. Curr. Sci., 79, 219-222, 2000.
57. Dong, H., Gou, Y. L., Kini, R. M., Xu, H. X., Chen, S. X., Teo, S. L. M. and But, P. P. H.: A new cytotoxic polyhydroxysterol from soft coral Sarcophyton trocheliophorum. Chem. Pharm. Bull. 48, 1087-1089, 2000.
58. Balaji, R. A., Ohtake, A., Sato, K., Gopalakrishnakone, P., Kini, R. M., Seow, K. T. and Bay, B. H.: Conotoxins, a new family of conotoxins with unusual disulfide pattern and protein folding: Isolation and characterization from the venom of Conus mormoreus. J. Biol. Chem., 275, 39516-39522, 2000.
59. Kuhn, P., Deacon, A. M., Comoso, D. S., Rajaseger, G. Kini, R. M., Uson, I. and Kolatkar P. R.: The atomic resolution structure of a novel toxin, bucandin, isolated from the Malayan krait, determined by direct methods. Acta Crystallographica, Series, 56D, 1401-1407, 2000.
60. Strong, P. N., Clark, G. S., Armugam, A., De-Allie, F. A., Joseph, J. S., Yemul, V., Deshpande, J. M., Kamath, R., Gadre, S. V., Gopalakrishnakone, P., Kini, R. M., Owen, D. G. and Jeyaseelan, K.: Tamulustoxin: a novel potassium channel blocker from the venom of the Indian red scorpion Mesobuthus tamulus. Arch. Biochem. Biophys. 385, 138-144, 2001.
61. Gao, R., Kini, R. M., Li, G., Luo, R., Selvanayagam, Z. E. and Gopalakrishnakone, P.: Purification and properties of three new phospholipase A2 isoenzymes from Micropechis ikaheka venom. Biochim. Biophys. Acta 1545, 30-40, 2001.
62. Srinivasan, K.N., Nirthanan, S., Sasaki, T., Sato, K., Cheng, B., Gwee, M.C.E., Kini, R.M., and Gopalakrishnakone, P.: Functional site of bukatoxin, an -type sodium channel neurotoxin from the chinese scorpion (Buthus martensi Karsch) venom: probable role of 52PDKVP56 loop. FEBS Lett. 494, 145-149, 2001.
63. Tan, D. C.-W., Kini, R. M., Jois, S. D. S., Lim, D. K. F. and Ge, R.: A small peptide derived from Flt-1 (VEGFR-1) functions as a potent angiogenic inhibitor. FEBS Lett. 494, 150-156, 2001.
64. Chua, Y. L., Pwee, K. H. and Kini, R. M.: DNA-binding mediated by the wheat HMGa protein: a novel instance of selectivity against alternating GC. Plant Mol. Biol. 46, 193-204, 2001.
65. Parvathy V. R., Chary, K. V. R., Kini, R. M. and Govil, G.: Sequence specific 13C NMR assignments in a neurotoxin (candoxin) from Bungarus candidus. Magn. Reson. Chem. 39, 577-580, 2001.
66. Torres, A. M., Kini, R. M., Nirthanan, S. and Kuchel, P. W.: NMR structure of bucandin, a neurotoxin from the venom of the Malayan krait. Biochem. J. 360, 539-548, 2001.
67. Srinivasan, K. N., Gopalakrishnakone, P., Tan, P. T., Chew, K. C., Cheng, B., Kini, R. M., Koh, J. L. Y., Seah, S. H. and Brusic, V. SCORPION, a molecular database of scorpion toxins. Toxicon 40, 23-31, 2002.
68. Joseph, J. S., Chung, M. C. M., Mirtschin, P. J. and Kini, R. M.: Effect of snake venom procoagulants on snake plasma: implications for the coagulation cascade of snakes. Toxicon 40, 175-183, 2002.
69. Nirthanan, S., Gao, R., Gopalakrishnakone, P., Gwee, M. C. E., Khoo, H. E., Cheah, L. S. and Kini, R. M.: Pharmacological characterization of mikatoxin, an a-neurotoxin isolated from a snake (Micropechis ikaheka) venom. Toxicon 40, 863-871, 2002.
70. Fry, B. G., Wickramaratna, J., Hodgson, W. C., Alewood, P. F., Kini, R. M.. Ho, H. and Wüster, W.: Electrospray LC-MS fingerprinting of Acanthophis (Death Adder) venoms: taxonomic and toxinological implications. Rapid Commun. Mass Spec. 16, 600-608, 2002.
71. Lakshminarayanan, R., Kini, R. M. and Valiyaveettil, S.: Investigation of the role of ansocalcin in the biomineralization in goose eggshell matrix. Proc. Natl. Acad. Sci., USA 99, 5155-5159, 2002.
72. Nirthanan, S., Charpantier, E., Gopalakrishnakone, P., Gwee, M. C. E., Khoo, H. E., Cheah, L. S., Bertrand, D. and Kini, R. M.: Candoxin, a novel toxin from Bungarus candidus is a reversible antagonist of muscle () but a poorly reversible antagonist of neuronal 7 nicotinic acetylcholine receptors. J. Biol. Chem. 277, 17811-17820, 2002.
73. Srinivasan, K. N., Sivaraja, V., Huys, I., Sasaki, T., Cheng, B., Kumar, T. K. S., Sato, K., Tytgat, J., Yu, C., Brian Chia, C. S., Ranganathan, S., Bowie, J. H., Kini, R. M. and Gopalakrishnakone, P.: Hefutoxin1, a novel toxin from the scorpion Heterometrus fulvipes with unique structure and function: importance of the functional diad in potassium channel selectivity. J. Biol. Chem. 277, 30040-30047, 2002.
74. Rao, V. S. and Kini, R. M.: Pseutarin C, a prothrombin activator from Pseudonaja textilis venom: Its structural and functional similarity to mammalian coagulation factor Xa-Va complex. Thrombos. Haemos. 88, 611-619, 2002.
75. Watanabe, L., Nirthanan, S., Rajaseger, G., Polikarpov, I., Kini, R. M. and Arni, R. K.: Crystallization and preliminary X-ray analysis of bucain, a novel toxin from the Malayan krait Bungarus candidus. Acta Crystallogr. Section D, 58, 1879-1881, 2002.
76. Gao, R., Kini, R. M. and Gopalakrishnakone, P.: A novel prothrombin activator from the venom of Micropechis ikaheka: isolation and characterization. Arch. Biochem. Biophys. 408, 87-92, 2002.
77. Zhang, W., Wu, Q., Pwee, K. H. and Kini, R. M.: Interaction of wheat migh-mobility-group proteins with four-way-junction DNA and Characterization of structure and expression of HMGA gene. Arch. Biochem. Biophys. 409, 357-366, 2002.
78. Pedarzani, P., D'hoedt, D., Doorty, K. B., Wadsworth, J. D. F., Joseph, J. S., Jeyaseelan, K., Kini, R. M., Gadre, S. V., Sapatnekar, S. M., Stocker, M. and Strong, P. N.: Tamapin: a venom peptide from the Indian red scorpion (Mesobuthus tamulus) which targets small conductance Ca2+-activated K+ channels and afterhyperpolarization currents in central neurons. J. Biol. Chem. 277, 46101-46109, 2002.
79. Rao, V. S., Joseph, J. S. and Kini, R. M.: Group D prothrombin activators from snake venom are structural homologues of mammalian blood coagulation factor Xa. Biochem. J. 369, 635-642, 2003.
80. Lakshminarayanan, R., Valiyaveettil, S. Rao, V. S. and Kini, R. M.: Purification, characterization, and in vitro mineralization studies of a novel goose eggshell matrix protein, ansocalcin. J. Biol. Chem. 278, 2928-2936, 2003.
81. Wickramaratna, J. C., Fry, B. G., Aguilar, M. I., Kini, R. M. and Hodgson, W. C.: Isolation and pharmacological characterisation of a phospholipase A2 myotoxin from the venom of the Irian Jayan death adder (Acanthophis rugosus). Brit. J. Pharmacol. 138, 333-342, 2003.
82. Joseph, J. S., Valiyaveettil, M., Gowda, D. C. and Kini, R. M.: Occurrence of O-linked Xyl-GlcNAc and Xyl-Glc disaccharides in trocarin, a factor Xa homolog from snake venom. J. Thrombos. Haemos. 1, 545-550, 2003.
83. Paaventhan, P., Joseph, J. S., Nirthanan, S., Rajaseger, G., Kini, R. M. and Kolatkar, P. R.: Crystallization and preliminary X-ray analysis of candoxin, a novel reversible neurotoxin from the Malayan krait Bungarus candidus. Acta Crystallogr. Section D, 59, 589-562, 2003.
84. Nirthanan S., Charpantier, E., Gopalakrishnakone, P., Gwee, M. C. E., Khoo, H. E., Cheah, L. S., Bertrand, D. and Kini, R. M.: Neuromuscular effects of candoxin, a novel toxin from the venom of the Malayan krait (Bungarus candidus). Brit. J. Pharmacol. 139, 832-844, 2003.
85. Rao, V. S., Swarup, S. and Kini, R. M.: The nonenzymatic subunit of pseutarin C, a prothrombin activator from common brown snake (Pseudonaja textilis) venom, shows structural similarity to mammalian coagulation factor V. Blood, 102, 1347-1354, 2003.
86. Zhang, W., Wu, Q., Pwee, K. H., Jois, S. D. S. and Kini, R. M.: Characterization of the interaction of wheat HMGa with linear and four-way junction DNAs. Biochemistry, 42, 6596-6607, 2003.
87. Fry, B. G., Wüster, W., Kini, R.M., Brusic, V., Khan, A., Venkataraman, D., Rooney, A. P.: Molecular evolution and phylogeny of elapid snake venom three finger toxins. J. Mol. Evol., 57, 110-129, 2003.
88. Fry, B. G., Lumsden, N. G., Wüster, W., Wickramaratna, J. C., Hodgson, W. C. and Kini, R. M.: Isolation of a neurotoxin (-colubritoxin) from a ‘non-venomous’ colubrid: evidence for early origin of venom in snakes. J. Mol. Evol., 57, 446-452, 2003.
89. Ajikumar, P. K., Lakshminarayanan, R., Ong, B. T., Valiyaveettil, S. and Kini, R. M.: Eggshell matrix protein mimics: Designer peptides to induce the nucleation of calcite crystal aggregates in solution. Biomacromolecules, 4, 1321-1326, 2003.
90. Torres, A. M., Wong, H. Y., Desai, M., Moochhala, S., Kuchel, P. W. and Kini, R. M.: Identification of a novel family of proteins in snake venoms: purification and structural characterization of nawaprin from Naja nigricollis snake venom. J. Biol. Chem., 278, 40097-40104, 2003.
91. Joseph, J. S., Thirumangalathu, S., Tsang, F., Wong, F. W. S. and Kini, R. M.: Trocarin, a blood coagulation factor Xa homologue from snake venom, causes inflammation and mitogenesis. Toxicon, 42, 769-776, 2003.
92. Fry, B. G., Wuster, W., Ramjan, R. S. F., Jackson, T., Martelli, P. and Kini, R. M.: Analysis of Colubroidea snake venoms by liquid chromatography with mass spectrometry: evolutionary and toxinological implications. Rapid Commun. Mass Spectrom., 17, 2047-2062, 2003.
93. Lumsden, N. G., Fry, B. G., Kini, R. M. and Hodgson, W. C.: In vitro neuromuscular activity of 'colubrid' venoms: clinical and evolutionary implications. Toxicon, 43, 819-827, 2004.
94. Rao, V. S., Swarup, S. and Kini, R. M.: The catalytic subunit of pseutarin C, a group C prothrombin activator from the venom of Pseudonaja textiles, is structurally similar to mammalian blood coagulation factor Xa. Thrombos. Haemostas., 92, 509-521, 2004.
95. Lumsden, N. G., Fry, B. G., Ventura, S., Kini, R. M. and Hodgson, W. C.: The in vitro and in vivo pharmacological activity of Boiga dendrophila (Mangrove Catsnake) venom. J. Autonom. Autocoid Pharmacol., 24, 107-113, 2004.
96. Li, M., Fry, B. G. and Kini, R. M.: Eggs-only diet: Its implications for the toxin profile changes and ecology of the marbled sea snake (Aipysurus eydouxii). J. Mol. Evol., 60, 81-89, 2005.
97. Reza, M. A., Swarup, S. and Kini, R. M.: Two parallel prothrombin activator systems in Australian rough scaled snake (Tropidechis carinatus): structural comparison of venom prothrombin activator with blood coagulation factor X. Thrombos. Haemostas., 93, 40-47, 2005.
98. Kini, R. M. and Banerjee, Y.: Dissection approach: a simple strategy for identification of the step of action of anticoagulant agents in the blood coagulation cascade. J. Thrombos. Haemostas., 3, 170-171, 2005.
99. Lakshminarayanan, R., Joseph, J. S., Kini, R. M. and Valiyaveettil, S.: Structure-function relationship of avian eggshell matrix proteins: a comparative study of two major eggshell matrix proteins, ansocalcin and OC-17. Biomacromolecules, 6, 741-751, 2005.
100. Li, M., Fry, B. G. and Kini, R. M.: Putting the brakes on snake venom evolution: the unique molecular evolutionary patterns of Aipysurus eydouxii (Marbled sea snake) phospholipase A2 toxins. Mol. Biol. Evol., 22, 934-941, 2005.
101. Lumsden, N. G., Fry, B. G., Ventura, S., Kini, R. M. and Hodgson, W. C.: Pharmacological characterisation of a neurotoxin from the venom of Boiga dendrophila (Mangrove snake). Toxicon, 45, 329-334, 2005.
102. Le, T. N. M., Reza, M. A., Swarup, S. and Kini, R. M.: Gene duplication of coagulation factor V and origin of venom prothrombin activator in Pseudonaja textilis snake. Thrombos. Haemostas., 93, 420-429, 2005.
103. Pung, Y. F., Wong, P. T. H., Kumar, P. P., Hodgson, W. C. and Kini, R. M.: Ohanin, a novel protein from king cobra venom induces hypolocomotion and hyperalgesia in mice. J. Biol. Chem., 280, 13137-13147, 2005.
104. Lakshminarayanan, R., Ooi, E. C. J., Loh, X. J., Kini, R. M. and Valiyaveettil, S.: Purification and characterization of a vaterite inducing peptide, pelovaterin, from the eggshells of Pelodiscus sinensis (Chinese softshell turtle). Biomacromolecules, 6, 1429-1437, 2005.
105. Sulochana, K. N., Fan, H., Jois, S. D. S., Vivekanandan, S., Sun, F., Kini, R. M. and Ge, R.: Peptides derived from human decorin leucine rich repeat 5 inhibit angiogenesis. J. Biol. Chem., 280, 27935-27948, 2005.
106. Ajikumar, P. K., Vivekanandan, S., Lakshminarayanan, R., Jois, S. D. S., Kini, R. M. and Valiyaveettil, S.: Mimicking the Function of Eggshell Matrix Proteins: Role of Multiplets of Charged Amino Acid Residues and Self-Assembly of Peptides in Biomineralization. Angew. Chem. Int. Ed., 44, 5476-5479, 2005. (Featured in Nature Materials Aug 18 2005. http://www.nature.com/materials/news/news/050818/portal/m050818-1.html)
107. Mitra, N., Sinha, S., Kini, R.M. and Surolia, A.: Analysis of the peanut agglutinin molten globule-like intermediate by limited proteolysis. Biochim. Biophys. Acta General Subjects, 1725, 283-289, 2005.
108. Kang, T. S., Vivekanandan, S., Jois, S. D. S. and Kini, R. M.: Effect of C-terminal Amidation in Folding and Disulfide-Pairing of -Conotoxin ImI. Angew. Chem. Int. Ed., 44, 6333-6337, 2005.
109. Kuruppu, S., Banerjee, Y., Kini, R. M. and Hodgson W. C.: Isolation and pharmacological characterisation of cannitoxin, a presynaptic neurotoxin from the venom of the Papuan taipan (Oxyuranus scutellatus canni). J. Pharmacol. Exp. Ther., 315, 1196-1202, 2005.
110. Banerjee, Y., Mizuguchi, J., Iwanaga, S. and Kini, R. M.: Hemextin AB complex – a unique anticoagulant protein complex from Hemachatus haemachatus (African Ringhals cobra) venom that inhibits clot initiation and factor VIIa activity. J. Biol. Chem., 280, 42601-42611, 2005.
111. Pung, Y. F., Kumar, S. V., Rajagopalan, N., Kumar, P. P. and Kini, R. M.: Ohanin, a novel protein from king cobra venom: Its cDNA and genomic organization. Gene, 371, 246-256, 2006.
112. Reza, M. A., Le, T. N. M., Swarup, S. and Kini, R. M.: Molecular evolution caught in action: gene duplication and evolution of molecular isoforms of prothrombin activators in Pseudonaja textilis (brown snake). J. Thrombos. Haemostas., 4, 1346-1353, 2006.
113. Pawlak, J. and Kini, R. M.: Snake venom glutaminyl cyclase. Toxicon, 48, 278-286, 2006.
114. Kang, T. S., Jois, S. D. S. and Kini, R. M.: Solution structures of two structural isoforms of CMrVIA /-conotoxin. Biomacromolecules, 7, 2337-2346, 2006.
115. Pawlak, J., Mackessy, S. P., Fry, B. G., Bhatia, M., Mourier, G., Fruchart-Gaillard, C., Servent, D., Ménez, R., Stura, E., Ménez, A. and Kini, R. M.: Denmotoxin, a Three-finger Toxin from the Colubrid Snake Boiga dendrophila (Mangrove Catsnake) with Bird-specific Activity. J. Biol. Chem., 281, 29030-29041, 2006.
116. Lakshminarayanan, R., Loh, X. J., Gayathri, S., Sindhu, S., Banerjee, Y., Kini, R. M. and Valiyaveettil, S.: Formation of transient amorphous calcium carbonate precursor in quail eggshell mineralization - an in vitro study. Biomacromolecules, 7, 3202-3209, 2006.
117. Parvathy V., R., Chary, K. V. R., Kini, R. M. and Govil, G.: Solution structure of candoxin, a novel three-finger toxin from the venom of Bungarus candidus. Arkivoc, 2006, 1-16, 2006.
118. Reza, M. A., Swarup, S. and Kini, R. M.: Gene structures of two functionally diverse prothrombin activators, Trocarin D and coagulation factor X in Tropidechis carinatus snake: gene duplication and recruitment of factor X gene to the venom gland. J. Thrombos. Haemostas., 4, in press, 2006.
119. Gayathri, S., Lakshminarayanan, R., Weaver, J. C., Morse, D. E., Kini, R. M. and Valiyaveettil, S.: An in vitro study of magnesium-calcite biomineralization in the skeletal materials of seastar, Pisaster giganteus. Chem. Eur. J., in press, 2006.
120. Nair, D. G., Fry, B. G., Alewood, P., Kumar, P. P. and Kini, R. M.: Antimicrobial activity of omwaprin, a new member of waprin family of snake venom proteins. Biochem. J., in press, 2006.
121. Lumsden, N. G., Banerjee, Y., Kini, R. M., Kuruppu, S. and Hodgson, W. C.: Isolation and characterization of rufoxin, a novel protein exhibiting neurotoxicity from the venom of Psammophiine, Rhamphiophis oxyrhynchus (Rufous beaked snake). Neuropharmacology, in press, 2006.
122. Kang, T. S., Radic, Z., Talley, T. T., Jois, S. D. S., Taylor, P. and Kini, R. M.: Protein folding determinants: structural features determining alternative disulfide pairing in - and -conotoxins. Biochemistry, in press, 2007.

Review Papers:
1. Kini, R.M. and Evans, H.J.: Review article: Effects of snake venom proteins on blood platelets. Toxicon, 28, 1387-1422, 1990.
2. Gwee, M. C. E., Cheah, L. S., Gopalakrishnakone, P., Wong, P. T. H., Gong, J. P. and Kini, R. M.: Studies on venoms from the black scorpion Heterometrus longimanus and some other scorpion species. J. Toxicol.-Toxin Rev., 15, 35-57, 1996.
3. Kini, R. M.: Proline brackets and identification of potential functional sites in proteins: toxins to therapeutics. Toxicon 36, 1659-1670, 1998.
4. Chow, G. and Kini, R. M.: Exogenous factors from animal sources that induce platelet aggregation. Thrombos. Haemostas. 85, 177-178, 2001. See also http://www.med.unc.edu/isth/exogenous/exogfact.htm
5. Kini, R.M. and Chow, G.: Exogenous inhibitors of platelet aggregation from animal sources. Thrombos. Haemostas. 85, 179-181, 2001. See also http://www.med.unc.edu/isth/exogenous/exogfact.htm
6. Kini, R.M., Morita, T. and Rosing, J.: Classification and nomenclature of prothrombin activators isolated from snake venoms. Thrombos. Haemostas. 85, 710-711, 2001. See also http://www.med.unc.edu/isth/snake.htm
7. Kini, R. M., Rao, V. S. and Joseph, J. S.: Procoagulant proteins from snake venoms. Haemostasis, 31, 218-224, 2002.
8. Joseph, J. S., Rao, V. S. and Kini, R. M.: Snake venom prothrombin activators homologous to blood coagulation factor Xa. Haemostasis, 31, 234-240, 2002.
9. Mounier, C., Bon, C. and Kini, R. M.: Anticoagulant venom and mammalian secreted phospholipases A2: protein- versus phospholipid-dependent mechanism of action. Haemostasis, 31, 279-287, 2002.
10. Kini, R. M.: Molecular molds with multiple missions: functional sites in three-finger toxins. Clinic. Exptl. Pharmacol. Physiol. 29, 815-822, 2002.
11. Gwee, M. C. E., Nirthanan, S., Khoo, H. E., Gopalakrishnakone, P., Kini, R. M. and Cheah, L. S.: Autonomic effects of some scorpion venoms and toxins. Clinic. Exptl. Pharmacol. Physiol. 29, 795-801, 2002.
12. Nirthanan, S., Gopalakrishnakone, P., Gwee, M. C. E., Khoo, H. E. and Kini, R. M.: Non-conventional toxins from elapid venoms. Toxicon, 41, 397-407, 2002.
13. Kini, R. M.: Excitement ahead: structure, function and mechanism of snake venom phospholipase A2 enzymes. Toxicon, 42, 827-840, 2003.
14. Kini, R. M.: Platelet aggregation and exogenous factors from animal sources. Curr. Drug Targets Cardiovasc. Haematol. Dis., 4, 301-325, 2004.
15. Joseph, J. S. and Kini, R. M.: Snake venom prothrombin activators similar to blood coagulation factor Xa. Curr. Drug Targets Cardiovasc. Haematol. Dis., 4, 397-416, 2004.
16. Joseph, R., Pahari, S., Hodgson, W. C. and Kini, R. M.: Hypotensive agents from snake venoms. Curr. Drug Targets Cardiovasc. Haematol. Dis., 4, 437-459, 2004.
17. Kini, R. M.: The intriguing world of prothrombin activators from snake venoms. Toxicon, 45, 1133-1145, 2005.
18. Kini, R. M.: Structure-function relationships and mechanism of anticoagulant phospholipase A2 enzymes from snake venoms. Toxicon, 45, 1147-1161, 2005.
19. Banerjee, Y., Mizuguchi, J., Iwanaga, S. and Kini, R. M.: Hemextin AB complex - a snake venom anticogulant protein complex that inhibits Factor VIIa activity. Pathophysiol. Haemos. Thrombos., 34, 184-187, 2005.
20. Kini, R. M.: Serine proteinases affecting blood coagulation and fibrinolysis from snake venom. Pathophysiol. Haemos. Thrombos., 34, 200-204, 2005.
21. Reza, M. A., Swarup, S. and Kini, R. M.: Gene structures of trocarin D and coagulation factor X, two functionally diverse prothrombin activators from Australian rough scaled snake. Pathophysiol. Haemos. Thrombos., 34, 205-208, 2005.
22. Reza, M. A. and Kini, R. M.: Prothrombin activators from Australian snakes. Toxin Rev., 25, 257-290, 2006.
23. Kini, R. M.: Anticoagulant Proteins from Snake Venoms: Structure, Function and Mechanism. Biochem. J., 397, 377-387, 2006.


Book Chapters:
1. Shaha, C., Kaul, S., Kini, M., Chaudhury, M., Anand, R., Das, C and Talwar, G. P. (1986) Immunization against LHRH without the use of Freund's complete adjuvant. In: Reproductive Biology: Immunological Approaches to Contraception and Promotion of Fertility, Talwar, G. P. (Ed.), Plenum Press, New York, USA, pp. 143-150.
2. Kini, R.M., Stefansson, S. and Evans, H.J.: Non phospholipase anticoagulants from Naja nigricollis venom. In: Progress in Venom and Toxin Research, Gopalakrishnakone, P. and Tan, C.K. (Eds.), National University of Singapore, Singapore, pp.175 185, 1987.

3. Kini, R. M. and Evans, H. J.: A common structural feature enclosing interaction sites: prediction of protein-protein interaction sites and development of potent bioactive peptides. In: Current Topics in Peptide and Protein Research Menon, J. (Ed) Council of Scientific Information, Trivandrum, India, Vol. 1, pp. 297-311, 1994.


4. Kini, R. M.: Phospholipase A2 - A complex multifunctional protein puzzle. In: Venom Phospholipase A2 Enzymes: Structure, Function and Mechanism, Kini, R. M. (Ed) John Wiley, Chichester, England, pp. 1-28, 1997.
5. H. J. Evans and Kini, R. M.: Anticoagulant effects of phospholipases. In: Venom Phospholipase A2 Enzymes: Structure, Function and Mechanism, Kini, R. M. (Ed) John Wiley, Chichester, England, pp. 353-368, 1997.
6. Kini, R. M. and Evans, H. J.: Effects of phospholipase enzymes on platelet aggregation. In: Venom Phospholipase A2 Enzymes: Structure, Function and Mechanism, Kini, R. M. (Ed) John Wiley, Chichester, England, pp. 369-387, 1997.
7. Kini, R. M.: Snake venom phospholipase A2 enzymes in cell biology. In: Methods and Tools in Biosciences and Medicine: Animal Toxins. Rochat, H and Martin-Eauclaire, M. F. (Eds) Birkhauser, Verlag, Basel, Switzerland, pp. 304-318, 2000.
8. Kini, R. M., Joseph, J. S. and Rao, V. S.: Prothrombin activators from snake venoms. In: Perspectives in Molecular Toxinology. Mènez, A. (Ed) John Wiley, Chichester, England, pp. 341-355, 2002.


Conference Papers:

1. Kini, R.M. and Gowda, T.V.: Interaction of gymnemic acid with Naja naja venom proteins. 50th Annual Meeting of Society of Biological Chemists (India) held at Baroda, 1981.


2. Kini, R.M. and Gowda, T.V.: In vivo interaction of gymnemic acid with Naja naja venom and its purified neurotoxin. 51st Annual Meeting of Society of Biological Chemists (India) held at Chandigarh, 1982.

3. Kini, R.M.: Substrate specificity and the mechanism of action of phosphodiesterase from Trimeresurus flavoviridis venom. 54th Annual Meeting of Society of Biological Chemists (India) held at New Delhi, 1984.

4. Vishwanath, B.S., Kini, R.M. and Gowda, T.V.: Purification of an edema inducing phospholipase A2 from Vipera russelli venom and its interaction with aristolochic acid. 8th World Congress on Animal, Plant and Microbial Toxins held at New Castle upon Tyne, England. Toxicon, 23, 617, 1985.

5. Kini, R.M., Kawabata, S. and Iwanaga, S.: Amino acid sequence of the basic phospholipase A2 from the venom of Japanese habu (Trimeresurus flavoviridis). 58th Congress of Japanese Biochemical Society held at Sendai, Japan, 1986.

6. Kini, R.M. and Evans, H.J.: Structure function of phospholipases: the anticoagulant region of phospholipases A2. 1st Asia Pacific Congress on Animal, Plant and Microbial Toxins held at Singapore, Singapore. Toxicon, 26, 27 28, 1988.
7. Kini, R.M., Stefansson, S. and Evans, H.J.: Non phospholipase anticoagulants from Naja nigricollis venom. 1st Asia Pacific Congress on Animal, Plant and Microbial Toxins held at Singapore, Singapore. Toxicon, 26, 28, 1988.

8. Kini, R.M. and Evans, H.J.: Correlation between the enzymatic activity, anticoagulant and antiplatelet effects of phospholipase A2 isoenzymes from Naja nigricollis crawshawii venom. 9th World Congress on Animal, Plant and Microbial Toxins held at Stillwater, Oklahoma, U.S.A., 1988. Toxicon, 27, 55, 1989.

9. Stefansson, S., Kini, R.M. and Evans, H.J.: A basic phospholipase A2 from Naja nigricollis crawshawii venom inhibits thrombin formation by the prothrombinase complex. 9th World Congress on Animal, Plant and Microbial Toxins held at Stillwater, Oklahoma, U.S.A., 1988. Toxicon, 27, 79, 1989.

10. Kini, R.M. and Evans, H.J.: Role of cationic residues in the cytolytic and antiplatelet activity of a cardiotoxin from Naja nigricollis venom. Joint Meeting of the American Society for Cell Biology and the American Society for Biochemistry and Molecular Biology held at San Francisco, California, U.S.A., 1989. J. Cell Biol., 107, 855a, 1988.


11. Gong, J. P., Kini, R. M., Gwee, M. C. E. and Gopalakrishnakone, P.: Pharmacological activity of four fractions isolated from the venom of the scorpion Buthus martensi Karasch. First Asia-Pacific Colloquium in Neuroscience held at Singapore, 1994.
12. Fung, F. M. Y., Kini, R. M. and Ding, J. L.: Bioactive compounds from the mucus of the coral Galaxea fascicularis. Fourth Pacific Rim Biotechnology Conference held at Melbourne, Australia, 1995.
13. Gong, J. P., Kini, R. M., Gopalakrishnakone, P. and Gwee, M. C. E.: Separation and fractionation of toxins from the scorpion Buthus martensi Karasch. Third International Union of Biochemistry and Molecular Biology Conference held at Singapore, 1995. Toxicon, 33, 1398, 1995.
14. Kini, R. M.: A common structural feature enclosing protein-protein interaction sites: prediction of interaction sites and development of potent bioactive peptides. Third International Union of Biochemistry and Molecular Biology Conference held at Singapore, 1995. Toxicon, 33, 1400, 1995.
15. Kini, R. M.: Do we know the complete sequence of metalloproteinase and nonenzymatic platelet aggregation inhibitor (disintegrin) precursor proteins? Fifth Pan American Symposium on Animal, Plant and Microbial Toxins held at Fort Detrick, Maryland, USA, 1995. Toxicon, 34, 287, 1996.
16. Kini, R. M.: Purification and characterization of anticoagulants from Austrelaps superbus (copperhead) snake venom. Fifth Pan American Symposium on Animal, Plant and Microbial Toxins held at Fort Detrick, Maryland, USA, 1995. Toxicon, 34, 321, 1996.
17. Gong, J. P., Kini, R. M., Gwee, M. C. E. and Gopalakrishnakone, P.: Isolation of a purified toxin (martoxin, MTX) from the venom of the scorpion Buthus martensi Karsch with adrenergic and NANC actions. Fifth Pan American Symposium on Animal, Plant and Microbial Toxins held at Fort Detrick, Maryland, USA, 1995. Toxicon, 34, 330, 1996.
18. Gong, J. P., Kini, R. M., Gwee, M. C. E. and Gopalakrishnakone, P.: Biochemical and pharmacological characterization of a purified toxin (martoxin, MTX) from the venom of the scorpion Buthus martensi Karsch. 5th Inetranational Symposium on Neurobiology held at Mayaguez, Puerto Rico, 1995.
19. Huang, M., Chung, M., Kini, R. M. and Gopalakrishnakone, P.: The complete amino acid sequence of an acidic phospholipase A2 from the venom of Ophiophagus hannah. 1st Asia-Pacific Anatomical Conference held at Singapore, 1995. Toxicon, 34, 623-624, 1996.
20. Chen, D. S., Ghadessey, F. G., Khoo, H. E., Kini, R. M. and Yuen, R.: Role of free thiols in the biological properties of stonustoxin. 4th Asia-Pacific Congress on Animal, Plant and Microbial Toxins held at Kunming, Yunnan, China, 1996.
21. R. Yuen, Chen, D. S., Ghadessy, F. G., Khoo, H. E. and Kini, R. M.: Role of cationic residues in the haemolytic activity of stonustoxin. 4th Asia-Pacific Congress on Animal, Plant and Microbial Toxins held at Kunming, Yunnan, China, 1996.
22. Huang, M. Z., Gopalakrishnakone, P. and Kini, R. M.: Inhibition of human platelet aggregation by a phospholipase A2 platelet inhibitor from Ophiophagus hannah (King cobra) venom. 4th Asia-Pacific Congress on Animal, Plant and Microbial Toxins held at Kunming, Yunnan, China, 1996.
23. Gong, J. P., Kini, R. M., Gwee, M. C. E. and Gopalakrishnakone, P.: Prejunctional nitrergic effects of makatoxin I from scorpion (Buthus martensi Karsch) venom in the rat isolated anococcygeus muscle. 4th Asia-Pacific Congress on Animal, Plant and Microbial Toxins held at Kunming, Yunnan, China, 1996.
24. Gong, J. P., Kini, R. M., Gwee, M. C. E. and Gopalakrishnakone, P.: Makatoxin I (MkTx I): a new toxin purified from the venom of the scorpion Buthus martensi Karsch. 12th FAOBMB symposium held at Tokushima, Japan, 1996.
25. Shatursky, O. Ya., Kini, R. M., Venning, M. G., Hughes, B. P. and Bretag, A. H.: Venom of the death adder snake forms cation selective channels in bilayer lipid membrane. Third International Workshop on Pore-Forming Toxins held at Mainz, Germany, 1996.
26. Subburaju, S. and Kini, R. M.: Acanthin, a phospholipase A2 from Acanthophis antarcticus venom, inhibits platelet aggregation by a nonenzymatic mechanism. 16th Congress of the International Society on Thrombosis and Haemostasis held at Florence, Italy, 1997.
27. Sim, K. L. and Kini, R. M.: Purification and characterization of praelongins, antiplatelet phospholipases from the snake venom of Acanthophis praelongus. 16th Congress of the International Society on Thrombosis and Haemostasis held at Florence, Italy, 1997.
28. Huang, M. Z., Gopalakrishnakone, P. and Kini, R. M.: Mechanism of the antiplatelet effect of a phospholipase A2 (OHV A-PLA2) from the venom of Ophiophagus hannah (King cobra). 16th Congress of the International Society on Thrombosis and Haemostasis held at Florence, Italy, 1997.
29. Tan, B. K. H., Kini, R. M. and Gao, S. J.: Screening extracts of Pronephrium triphyllum and Moringa oleifera for anticoagulant activity. 7th SCBA International Symposium held at Toronto, Canada, 1997.
30. Kini, R. M.: Identification of potential functional sites in proteins: toxins to therapeutics. 12th World Congress on Animal, Plant and Microbial Toxins held at Cuernavaca, Mexico, 1997.
31. Gong, J. P., Gopalakrishnakone, P., Kini, R. M. and Gwee, M. C. E.: Capillary electrophoretic analysis of scorpion venoms. 12th World Congress on Animal, Plant and Microbial Toxins held at Cuernavaca, Mexico, 1997.
32. Gong, J. P., Gwee, M. C. E., Kini, R. M. and Gopalakrishnakone, P.: Chibutoxin, a novel toxin isolated from the venom of the scorpion Buthus martensii Karsch which inhibits adrenergic transmission. 12th World Congress on Animal, Plant and Microbial Toxins held at Cuernavaca, Mexico, 1997.
33. Armugam, A., Kok, S. L., Kini, R. M., Gopalakrishnakone, P., Tan, N. H. and Jeyaseelan, K.: Cloning and sequence analysis of genes encoding phospholipase A2 in the venom of Naja naja sputatrix. 12th World Congress on Animal, Plant and Microbial Toxins held at Cuernavaca, Mexico, 1997.
34. Huang, M. Z., Gopalakrishnakone, P. and Kini, R. M.: Mechanism of the effect of a phospholipase A2 platelet inhibitor from Ophiophagus hannah venom. 12th World Congress on Animal, Plant and Microbial Toxins held at Cuernavaca, Mexico, 1997.
35. Wang, R., Kini, R. M. and Chung, M. C. M.: Rhodocetin, a novel C-type lectin related protein from the venom of Calloselasma rhodostoma (Malayan pit viper). Institute of Molecular and Cell Biology Tenth Anniversary Symposium held at Singapore, 1997.


  1. Thwin, M. M., Gopalakrishnakone, P., Kini, R. M., Armugam, A. and Jeyaseelan, K.: An endogenous antitoxic factor from Python reticulatus serum: protein purification and cDNA cloning. An Inaugural Conference: From Venoms to Drugs held at Heron Island, Australia, 1998.




  1. Roma, S., Lim, C. Y., Armugam, A., Kini, R. M., Gopalakrishnakone, P., Strong, P. N. and Jeyaseelan, K.: Molecular cloning of a potassium channel blocking toxin gene from Indian Red Scorpion, Mesobuthus tamulus. An Inaugural Conference: From venoms to Drugs held at Heron Island, Australia, 1998.



  1   2   3


База данных защищена авторским правом ©shkola.of.by 2016
звярнуцца да адміністрацыі

    Галоўная старонка